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دیباچہ

دیباچہ
اللہ کے نام سے ابتداکرتا ہوں جو نہایت مہربان ،نہایت رحم کرنے والا ہے۔ تمام تعریفیں اللہ کی بابرکت ذات کے لیے ہیں جو لائقِ حمد وثنا ہے اور درودو سلام آپ صلی اللہ علیہ و آلہٖ وسلم اور آپ صلی اللہ علیہ و آلہٖ وسلم کی آل پر جن کے صدقے مجھ حقیر کو موقع ملا کہ ’’ڈاکٹر شہزاد احمد کی علمی و ادبی خدمات‘‘ پر تحقیق کر سکوں ۔اللہ تعالیٰ نے اس تحقیقی کام کوتکمیل آشنا کرنے کی توفیق عطا فرمائی،اس لیے اس پاک ذات کا جتنا بھی شکرادا کروں کم ہے۔ اُسی ذات نے دورانِ تحقیق آنے والی مشکلات کو دور کیا۔
رفاہ انٹرنیشنل یونی ورسٹی فیصل آباد کیمپس میں جن محنتی ، لائق اساتذہ کی سرپرستی میں کام کرنے کا موقع ملا؛ اُن میں ڈاکٹر آنسہ اعوان، ڈاکٹر منظور احمد طاہر، ڈاکٹر آصف اعوان ، ڈاکٹر جمیل اصغر، اخلاق حیدر آبادی اور فاروق بیگ کے نام نمایاں ہیں۔ انھیں ہستیوں کی شفقت کی بدولت طلبا میں علم کی شمع روشن ہے۔
ڈاکٹرشہزاداحمد شعبہ نعت کے نامور محقق ہیں،اس لیے میں نے اس موضوع کو مبارک خیال کرتے ہوئے کام کرنے کاارادہ کرلیا۔اس کے بعد کے مراحل میں میرے اُستادفاروق بیگ نے میری بھرپور راہنمائی فرمائی۔
میرا یہ مقالہ پانچ ابواب پر مشتمل ہے ۔ ’’ڈاکٹر شہزاد احمد: احوال و آثار‘‘میں موصوف کے نجی احوال ، نعتیہ خدمات، تخلیقات اور شخصیت کے نمایاں پہلوئوں کا احاطہ کیا گیا ہے۔ باب دوم ـ’’ شہزاداحمد بطور محقق و نقاد‘‘میں ڈاکٹر شہزاد احمد کے پی ایچ ڈی کے مقالے ’’اُردو نعت پاکستان میں‘‘ کا تحقیقی جائزہ پیش کیا ہے اس کے بعد اُن کے مضامین میں رنگِ تنقید کو نمایاں کرنے کی سعی کی گئی ہے۔ باب سوم’’ڈاکٹر شہزاداحمدبطور مدون ومدیر ‘‘میں اُن کی مرتب کردہ مختلف کلیات اور کتب کی روشنی میں بحیثیت مدون اُن...

Review of the Jihadi and Mystical Services of Maulana Muhammad Shoaib Tordheri

Allah has promised to protect Islam. That is why Allah created scholars and Sufis in different periods that served Islam and preached Islam. The preaching and propagation of Islam in India is due to these Sufis. They left their territories and came to India. One of these scholars and Sufis is Maulana Muhammad Shoaib Tordheri, known as Shaikh Sahib. He was the Shaikh of Moulana Abdul Ghafoor (Swat Babaji), that is the most famous Sufi in Swat Khyber Pakhtonkhwa and Shaikh of the Moulana Abdul Rahim Saharan Puri.  Moulana Muhammad Shoaib was not a scholar and sufi, he was also a mujahid. He was martyred while fighting against the Sikhs in 1823 A.D. He wrote a book about Sufism. In his book he wrote about seeratul Nabi and companion of Prophet Muhammad S.A.W. After that he discussed circumstances and sayings of Sufis of the all four series (Naqshbandia, Qadria, Cheshtia and Saharwardia) of Sufism. He also described the attributes of the perfect Peer.

Mapping of New Locus in Deafness

Deafness is the most prevalent disorder with 1 in every 500 of world population has disabled hearing loss. Deafness may occur in non-syndromic or syndromic form. Non-syndromic deafness accounts for 70% while remaining 30% accounts for syndromic deafness. Although deafness is prevalent worldwide but determination of causative genes is difficult due to genetic heterogeneity and limited genotype phenotype correlation of deafness related genes. An extensive research on deafness in the last two decades has paved remarkable progress in the detection of deafness related genes. In terms of nonsyndromic recessive hearing loss, the chromosomal locations are presently identified for ~102 loci recessive deafness, elucidating role of 63 genes having causative role in deafness. As nearly 300 genes are involved in hearing cascade a need of further study is the requirement for current study of deafness genetically. The present study was intended to ascertain the molecular basis of deafness expressed at different audiometric levels by making use of linkage analysis as a genetic tool. To attain the objective, Thirty five families with non-syndromic and syndromic phenotype segregating with autosomal recessive mode of inheritance were enrolled, after collection of blood samples DNA was extracted and linkage analysis was done for already reported autosomal recessive deafness loci. In eleven families having syndromic phenotype, four families showed linkage to Usher Syndrome Type 1D, three families showed linkage to Usher Syndrome Type 1F and one family was found linked to Usher Syndrome Type 2C whereas remaining three were found linked to DFNB4/PDS locus. All three Pendred syndrome linked families showed similar pattern of haplotype with DFNB4 Short Tandem Repeats markers. Interestingly on mutational analysis p.Y556C mutation was found in all affected individuals this finding outline this mutation as founder mutation in Punjabi ethnicity of Pakistani population mutation spectrum. In Five families with non- syndromic phenotype, one family was found linked to DFNB49 locus whereas four families were found linked to DFNB8/10, DFNB4, DFNB21 and DFNB7/11 loci. Sequence analysis of these linked families identified two reported mutations one c.1219T>C; p.C407R in TMPRSS3 gene (DFNB8/10) and other c.71G>T; p.R24L in SLC26A4 gene (DFNB4) whereas one novel mutation c.1247_1248delGG; p.G416Dfs*24 in TECTA gene (DFNB21) and a novel compound heterozygous mutation c.1259G>A; p.C420Y and c.1788C>A; p.S596R in TMC1 gene (DFNB7/11) was found. The genome scan of the family PKDF1629 having syndromic phenotype outlines a new recessive deafness locus hint at chromosome 6 position q23.3-25.2 with a critical linkage interval of 19.2Mb. This novel discovery will assist in better understanding of genetics involved in syndrome associated with deafness and will pave way for their diagnosis, treatment and eventually their control.
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