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بابے دی نیکی تے بندے غلط فہمی

بابے دی نیکی تے بندے غلط فہمی

کسے پنڈ وچ اک بزرگ رہندا سی۔ بہت اخلاق والا، نماز دا پابند تے دیانت دار، سارے لوک اوس بزرگ دی عزت کردے سن۔ لوک اوس کول بیٹھدے تے اوہ لوکاں نوں دین دا گلاں سنا کے اوہناں دی سدھے رستے اتے چلن دی راہنمائی کردا۔ اوس بزرگ کول اوہدے بزرگاں دا رسی دا اک ٹوٹا سی۔ جو اوس نوں بہت پیارا سی۔ ایہہ اوس دے والد نے اوہنوں دیندے ہوئے آکھیا کہ اوہدے والد نے اوہنوں دتا اے۔ ایہہ بہت برکت والا اے۔ توں ایس وچ لکڑیاں بنھ کے بازار ویچن لئی جایا کر۔ تیرے روزی وچ بہت برکت ہووے گی۔ بابا ہر ویلے اوس نوں اپنے کول رکھدا۔ جنگل وچوں لکڑیاں ودھ کے اوہ ایس رسّی وچ بنھدا تے شہر جا کے لکڑیاں ویچ آندا۔ اوس دیاں لکڑیاں چھیتی وِک جاندیاں تے گھر آ کے اوہ فیر لوکاں نوں وعظ نصیحت کرن لگ جاندا۔

اک دن اوس نوں نالے دے پنڈ چوں شادی دا سدا آیا۔ تے اوہ شادی والے گھر اپڑ گیا۔ بھیڑ وچ اک امیر آدمی دا پرس چوری ہو گیا جس وچ بہت سارے پیسے، کاغذات تے کجھ ہور چیزاں وی سن، سارے لوک اک دوجے اتے شک کرن لگ پئے۔ بزرگ نے شادی والیاں نوں پیسے دیون لئی جیب وچ ہتھ پایا تاں رسی دا اوہ ٹوٹا زمین تے ڈگ پیا۔ جدوں اوہ اوس نوں چک رہیا سی تاں اک بندے نے اوس نوں زمین اتوں کوئی چیز چکدے ویکھ لیا۔ اوس گھر دے مالک نوں دسیا کہ اوس بابے کول پرس اے۔ مالک نے بابے توں پچھن توں بغیر ای تھانے جا کے ساری گل تھانے دار نوں دس دتی۔

کجھ ای چر مگروں پولیس شادی والے گھر آ گئی۔ اوہناں بزرگ نوں پھڑ...

Analysis of Factors Influencing Procurement Fraud in Government Agencies Environment (Case Study at Regional Apparatus in “XYZ” Regency)

This study aims to examine factors such as the Quality of the Procurement Committee, Goods/Services Procurement Systems and Procedures, Goods/Services Procurement Ethics, and Goods/Services Procurement Environment against Fraud in the Procurement of Goods/Services in Government Agencies. The research method used in this study is a quantitative method. The population in this study was the Head of Service, Treasurer, and Head of Sub-Division of Finance, and the sample in this study was the Regional Work Unit in “XYZ” Regency. The source of the data used in this research is the main/primary data obtained directly from the questions/statements (questionnaires) distributed to the respondents. The data analysis method used in this study is the Statistical Program for Social Science (SPSS) to test the four hypotheses proposed in this study. The results of this study indicate that systems and procedures are proven to have a positive influence on procurement fraud in government agencies, while the quality of the Procurement Committee, Procurement Ethics, and the Procurement Environment are not proven to have a positive effect on procurement fraud in government agencies.  

Synthesis, Characterization and Biological Evaluation of Substituted Pyrazoles

In this dissertation, conditions were optimized to synthesize novel and more potent pyrazole derivatives from celecoxib, a well-known drug used to treat inflammation. The aim was to find future candidates that can be used in replacement with celecoxib because of the potential side effects of this drug. Three synthetic routes were established using easily available raw materials and easy to produce derivatives having high purity as well as experimental yield. In the first part of this study, 4-methyl group of celecoxib pharmacophore (3) was selectively oxidized. The product 4-{1-[4-(aminosulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-5-yl}benzoic acid (306) was esterified, followed by its hadrazinolysis to get 4-[5-(4-hydrazinocarbonyl-phenyl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide (308) which was further reacted with different reagents to produce the target pyrazoles. Substituted pyrazoles 309-326 were prepared by condensation of carbohydrazide (308) with different aromatic aldehydes. Keeping in view the potential biological activities of 1,2,4-triaozle and different pyarozles, the synergism of both the heterocyclic moieties in a single nucleus was introduced in the second part of this study. Compound 308 was converted to 4-(5-(4-(4-amino-5-mercapto-4H-1,2,4-triazol-3-yl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide (327) by reaction with carbon disulphide in alkaline ethanol followed by its hydrazinolysis, the product obtained was subsequently reacted with a number of benzaldehyde derivatives to afford the title compounds 328-340. In the third part of this study, chalcones prepared from substituted acetophenone and benzaldehyde derivatives were allowed to react with carbohydrazide (308) in acidified ethanol to produce the compounds 341-352. All the compounds were characterized by FT-IR, 1HNMR, mass and elemental analyses along with the single crystal X-ray crystallography of few compounds. The synthesized compounds were evaluated for their anti-inflammatory, ulcerogenic, anti-bacterial and anti-oxidant activities. Most of the compounds were found active against inflammation when Paw Oedema Model on albino Wistar rats. Few of the compounds (313, 314, 322, 329-331, 333-340) showed even greater anti-inflammation effect than the reference drug celecoxib along with no ulcerogenic effect. Similarly, many of these compounds were observed to be good anti-bacterial when tested against gram positive and gram negative bacteria. Many of the tested compounds also showed good anti-oxidant activity when compared with standard butylated hydroxytoluene (BHT) with few of them showing greater anti-oxidant potential than BHT.
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